Retin a an clindamicin

ZIANA® clindamycin phosphate 1.2% and tretinoin 0.025% Gel.

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Use of combinations of different classes of topical products—frequently antimicrobials and retinoids—is common in the management of acne vulgaris.

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Application of adapalene gel to the skin 3–5 minutes before application of clindamycin enhances penetration of clindamycin into the skin, which may enhance the overall efficacy of the treatment as compared to clindamycin alone. A study with six acne patients treated once daily for five days with two grams of adapalene cream applied to 1000 cm² of skin found no quantifiable amounts, or less than 0.35 ng/m L of the drug, in the patients' blood plasma.

Practical Dermatology - Clinical Experience Utilizing Topical.

(2009.) Optimizing use of oral antibiotics in acne vulgaris. Clindamycin and tretinoin topical medical facts from

Retin a an clindamicin:

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