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Metformin should be used with caution in: the elderly, those on a very low calorie diet or whom are likely to have surgery under general anaesthesia, or those with any liver problems, kidney problems, a heart disorder, or who drink alcohol to excess, those with sodium restricted diet It should not be used in: women who are breastfeeding, patients with any form of kidney problem or any conditions with the potential to alter renal function such as dehydration, severe infection, shock, or anyone having an injection of contrast agents containing iodine into their muscles; those with severe liver problems, are an alcoholic or are drunk; anyone with a condition that may result in a lack of oxygen in body organs (e.g.

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