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- Drugs That Inhibit Levothyroxine Absorption - Pharmacy Times
- WelChol oral Uses, Side Effects, Interactions, Pictures, Warnings.
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Reduction of elevated low-density lipoprotein (LDL) cholesterol (LDL-C) in adults with primary (Fredrickson type IIa) hyperlipidemia as adjunct to diet and exercise, either alone or in combination with a statin Tablet: 1.875 g (3 tablets) PO q12hr with meals or 3.75 g (6 tablets) PO once daily with a meal Oral suspension: 1.875 g (½ packet) PO q12hr or 3.75 g (1 packet) PO once daily, mixed with liquid Overdose: Symptoms include gastrointestinal (GI) obstruction; treatment is supportive Improvement of glycemic control in adults; taken in combination with insulin or oral antidiabetic agents Tablet: 1.875 g (3 tablets) PO q12hr with meals or 3.75 g (6 tablets) PO once daily with a meal Oral suspension: 1.875 g (½ packet) PO q12hr or 3.75 g (1 packet) PO once daily, mixed with liquid Overdose: Symptoms include GI obstruction; treatment is supportive Tablet: Take with meals and plenty of liquid Oral suspension: Empty packet in 4-8 oz of water, fruit juice, or diet soft drink and stir; drink with meal(s) May be coadministered with statins or administered at separate times Increased seizure activity or decreased phenytoin levels in patients receiving phenytoin; administer phenytoin 4 hours before colesevelam Reduced international normalized ratio (INR) in patients receiving warfarin; monitor INR Elevated thyroid-stimulating hormone (TSH) level in patients receiving thyroid hormone replacement therapy; administer thyroid hormones 4 hours before colesevelam GI: Bowel obstruction, dysphagia, esophageal obstruction, fecal impaction, pancreatitis, increased transaminase levels Dysphagia (use oral suspension; large tablets can obstruct esophagus) Not recommended in gastroparesis (constipating effects) Not for glycemic control in type I diabetes mellitus or diabetic ketoacidosis May reduce absorption of some drugs and nutrients; administer drugs with known interactions or narrow therapeutic index 4 hours before colesevelam Not studied in Fredrickson I, III, IV, or V hyperlipidemia May exacerbate preexisting constipation (initiate therapy at lower dosage in patients with history of constipation) Oral suspension contains phenylalanine Secondary causes of hyperlipidemia must be ruled out before therapy is initiated Can increase Tg level, particularly when used with insulin or sulfonylureas; marked hypertrlyceridemia can cause acute pancreatitis Bile acid sequestrants may decrease absorption of fat-soluble vitamins Forms complex with bile acids that is not absorbed through intestine; inhibits enterohepatic reuptake of intestinal bile salts, and this, in turn, increases fecal loss of bile salt-bound LDL and consequently reduces serum cholesterol in patients with primary hypercholesterolemia The above information is provided for general informational and educational purposes only.
WelChol colesevelam dosing, indications, interactions, adverse.
Colesevelam is used along with diet, weht loss, and exercise to reduce the amount of cholesterol and certain fatty substances in the blood.
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The thyroid medication levothyroxine (LEVO-T, LEVOXYL, NOVOTHYROX, SYNTHROID, THYRO-TABS, UNITHROID) is used to treat hypothyroidism, an endocrine disorder resulting from a thyroid homone deficiency that affects about 4.6 percent of the U. The number of prescriptions for levothyroxine filled each year—more than 75 million U. prescriptions in 2007 — makes it one of the mostprescribed drugs in the country.
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Colesevelam may interfere with the absorption of levothyroxine when these medications are taken at the same time.Welchol - Side Effects, Dosage, Interactions Everyday Health
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